Research reveals relationship between hypertension, gut bacteria, and sleep apnea. In the latest study, the researchers examined the link between sleep apnea, hypertension, and gut bacteria.
Sleep apnea is a potentially serious sleep disorder in which breathing stops and starts for periods throughout the night. Obstructive sleep apnea is the most common sleep-related breathing disorder. OSA can increase the risk of developing heart disease and depression. Research also suggests a link between OSA and endocrine disorders such as type 2 diabetes, neurological disorders including epilepsy, and hypertension.
High blood pressure affects around 1.28 billion people aged 30–79 globally.
The new research also shows that there is a relationship between sleep-disordered breathing and hypertension.
The latest review appears in the Journal of Clinical Sleep Medicine (JCSM).
“Long‐term active inflammation appears to be associated with a longitudinal increase of arterial stiffness. In turn, this longitudinal increase of arterial stiffness appears to be associated with longitudinal elevation of blood pressure to the hypertensive range,” researchers say.
For the findings, the scientists used a rat model of OSA. They didn’t found a link between OSA and the effect on blood pressure. However, in the high-fat OSA rats, the scientists also found dysbiosis with a reduction in butyrate-producing bacteria.
“These studies demonstrate a causal relationship between gut dysbiosis and hypertension, and suggest that manipulation of the microbiota may be a viable treatment for OSA-induced, and possibly other forms of, hypertension,” the study author concluded.
Although the investigation is ongoing, according to the authors, doctors may prescribe probiotics or prebiotics to reduce OSA-related hypertension.