High-fat diet may increase cardiovascular disease risk, according to a recent study. A high-fat diet interferes with the inner functioning of the gut and this may raise the risk of heart disease.
In the new study, the researchers examined the link between greasy diets, gut microbes, and the risk of developing heart diseases in mice.
A high-fat diet, involving plenty of fast food, increases the risk of cardiovascular diseases. This kind of diet disturbs the normal working of the gut and elevates the growth of harmful microbes.
Recently, researchers at Vanderbilt University Medical Center, in Nashville, TN, conducted a study to explain the link between high fat diets and the risk of developing cardiovascular diseases.
Their research findings appear in the journal Science.
The gut microbiota has a role in human health and the prevention of disease. disturbance in the regular functioning of gut microbiota may be associated with some medical conditions, such as irritable bowel syndrome obesity, and cardiovascular diseases.
The latest research in mice found that chronic consumption of a high-fat diet affects the intestinal epithelium and causes low-grade inflammation. It also reveals that a high-fat diet disturbs the functioning of the mitochondria.
“Our research is finding that the host cells, specifically the intestinal epithelium, play a crucial role in modulating the microbiota function, and can ‘turn on’ or ‘turn off’ metabolic pathways in the microbes that will directly affect risk for certain diseases,” study author Dr. Mariana Byndloss said.